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Effects of ipragliflozin on the development and progression of kidney disease in patients with type 2 diabetes: An analysis from a multicenter prospective intervention study
- Source :
- Journal of Diabetes Investigation, Vol 11, Iss 5, Pp 1248-1257 (2020), Journal of Diabetes Investigation
- Publication Year :
- 2020
- Publisher :
- Wiley, 2020.
-
Abstract
- Aims/Introduction Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long‐term treatments are available. Methods This was an investigator‐initiated multicenter prospective intervention study in which ipragliflozin (50 mg) was administered once daily, and glycemic control, estimated glomerular filtration rate (eGFR) and adverse events were evaluated until 104 weeks after starting research. Results There were 407 patients analyzed. In the eGFR ≥90 group and eGFR ≥60 to 300 group and the eGFR<br />In the estimated glomerular filtration rate (eGFR) ≥90 group and eGFR ≥60 to
- Subjects :
- Blood Glucose
Male
Sodium–glucose cotransporter 2 inhibitor
medicine.medical_specialty
Endocrinology, Diabetes and Metabolism
Urology
Renal function
030209 endocrinology & metabolism
Thiophenes
Diabetic nephropathy
Type 2 diabetes
030204 cardiovascular system & hematology
Diseases of the endocrine glands. Clinical endocrinology
03 medical and health sciences
chemistry.chemical_compound
0302 clinical medicine
Glucosides
Diabetes mellitus
Internal Medicine
medicine
Humans
Diabetic Nephropathies
Prospective Studies
Renal Insufficiency, Chronic
Adverse effect
Sodium-Glucose Transporter 2 Inhibitors
Aged
Glycemic
Glycated Hemoglobin
business.industry
Articles
General Medicine
Middle Aged
Prognosis
RC648-665
medicine.disease
Clinical Science and Care
Ipragliflozin
Diabetes Mellitus, Type 2
chemistry
Original Article
Female
business
Biomarkers
Follow-Up Studies
Glomerular Filtration Rate
Kidney disease
Subjects
Details
- ISSN :
- 20401124 and 20401116
- Volume :
- 11
- Database :
- OpenAIRE
- Journal :
- Journal of Diabetes Investigation
- Accession number :
- edsair.doi.dedup.....a859dbca969745a581dcb2e4382ca1ea