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Effects of ipragliflozin on the development and progression of kidney disease in patients with type 2 diabetes: An analysis from a multicenter prospective intervention study

Authors :
Akira Kanamori
Masahiro Takihata
Kotaro Iemitsu
Hikaru Amemiya
Mizuki Kaneshiro
Yoko Matsuzawa
Masashi Ishikawa
Keiji Tanaka
Hiroshi Takeda
Kazuaki Shinoda
Akira Kubota
Takehiro Kawata
Tetsuo Takuma
Nobuaki Minami
Yasushi Tanaka
Hideo Machimura
Ikuro Matsuba
Atsuko Mokubo
Masaaki Miyakawa
Masahiko Takai
Yasuo Terauchi
Syogo Ito
Taro Asakura
Fuyuki Minagawa
Source :
Journal of Diabetes Investigation, Vol 11, Iss 5, Pp 1248-1257 (2020), Journal of Diabetes Investigation
Publication Year :
2020
Publisher :
Wiley, 2020.

Abstract

Aims/Introduction Type 2 diabetes mellitus is the leading cause of kidney failure worldwide, but few effective long‐term treatments are available. Methods This was an investigator‐initiated multicenter prospective intervention study in which ipragliflozin (50 mg) was administered once daily, and glycemic control, estimated glomerular filtration rate (eGFR) and adverse events were evaluated until 104 weeks after starting research. Results There were 407 patients analyzed. In the eGFR ≥90 group and eGFR ≥60 to 300 group and the eGFR<br />In the estimated glomerular filtration rate (eGFR) ≥90 group and eGFR ≥60 to

Details

ISSN :
20401124 and 20401116
Volume :
11
Database :
OpenAIRE
Journal :
Journal of Diabetes Investigation
Accession number :
edsair.doi.dedup.....a859dbca969745a581dcb2e4382ca1ea