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Surgical management of giant secondary malignant fibrous histiocytoma following radiotherapy for nasopharyngeal carcinoma: A case report and literature review
- Source :
- Oncology Letters
- Publication Year :
- 2014
- Publisher :
- Spandidos Publications, 2014.
-
Abstract
- Malignant fibrous histiocytoma (MFH) is rare in the chest wall, particularly in patients who have undergone radiotherapy for primary nasopharyngeal cancer. In the present study, a case of MFH of the upper chest wall that appeared four years after initial radiotherapy for squamous cell carcinoma of the nasopharynx is reported. Furthermore, two-step surgical management was successfully performed consisting of i) tumor-reductive excision and ii) limb salvage surgery, including wide resection of the tumor mass, defect reconstruction of the chest wall using left latissimus dorsi myocutaneous flap and dermatoplasty of the flap-supplied region. The progress of the clinical characteristics, the reasons for radiation-induced carcinogenesis, the treatment options and the prognostic factors of MFH are also reviewed. Finally, the importance of prevention and follow-up of this malignancy are highlighted and specific advice is offered.
- Subjects :
- Cancer Research
Limb salvage surgery
medicine.medical_specialty
business.industry
surgical treatment
medicine.medical_treatment
Defect reconstruction
Cancer
Articles
malignant fibrous histiocytoma
medicine.disease
Malignancy
Surgery
Radiation therapy
Oncology
Nasopharyngeal carcinoma
medicine
In patient
business
radiotherapy
Nasopharyngeal cancer
Subjects
Details
- ISSN :
- 17921082 and 17921074
- Volume :
- 8
- Database :
- OpenAIRE
- Journal :
- Oncology Letters
- Accession number :
- edsair.doi.dedup.....a84daf920a6a94b728205a06a7a40a83