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A randomised controlled trial investigating the analgesic efficacy of transversus abdominis plane block for adult laparoscopic appendicectomy
- Publication Year :
- 2017
- Publisher :
- Singapore Medical Association, 2017.
-
Abstract
- Introduction We conducted a single-centre, prospective randomised clinical trial to investigate the analgesic efficacy of transversus abdominis plane (TAP) block in adult patients undergoing laparoscopic appendicectomy. Methods Patients undergoing urgent laparoscopic appendicectomy under general anaesthesia alone (control group) and general anaesthesia supplemented by TAP block (TAP intervention group) were compared. All patients received a multimodal analgesia regime, which included postoperative morphine via a patient-controlled analgesia device. The primary endpoints were morphine consumption at 12 hours and 24 hours postoperatively. Secondary endpoints included pain scores, incidence of nausea and vomiting, and time to hospital discharge. A total of 58 patients were recruited, with 29 patients in each group. Results Mean postoperative morphine consumption at 12 hours (control group: 11.45 ± 7.64 mg, TAP intervention group: 9.79 ± 8.09 mg; p = 0.4264) and 24 hours (control group: 13.38 ± 8.72 mg, TAP intervention group: 11.31 ± 8.66 mg; p = 0.3686) for the control and TAP intervention groups were not statistically different. Secondary outcomes were also not different between the two groups. Length of stay in the post-anaesthesia care unit was significantly shorter for the TAP intervention group, with a trend toward faster hospital discharge being observed. Conclusion TAP block, a regional anaesthetic procedure performed immediately prior to skin incision for laparoscopic appendicectomy, did not significantly improve postoperative analgesia outcomes.
- Subjects :
- Adult
Male
medicine.medical_specialty
Nausea
Analgesic
law.invention
03 medical and health sciences
0302 clinical medicine
Randomized controlled trial
030202 anesthesiology
Transversus Abdominis Plane Block
law
medicine
Appendectomy
Humans
General anaesthesia
030212 general & internal medicine
Abdominal Muscles
Pain, Postoperative
Morphine
business.industry
Analgesia, Patient-Controlled
Nerve Block
General Medicine
Surgery
Clinical trial
Anesthesia
Vomiting
Original Article
Female
Laparoscopy
medicine.symptom
business
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....a84401c15c4baf9de85ef0238d8b16df