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A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b)
- Source :
- Haas, David M; Parker, Corette B; Wing, Deborah A; Parry, Samuel; Grobman, William A; Mercer, Brian M; et al.(2015). A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b). American Journal of Obstetrics and Gynecology, 212(4), 539.e1-539.e24. doi: 10.1016/j.ajog.2015.01.019. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/983198g6
- Publication Year :
- 2015
- Publisher :
- eScholarship, University of California, 2015.
-
Abstract
- The primary aim of the "Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be" is to determine maternal characteristics, which include genetic, physiologic response to pregnancy, and environmental factors that predict adverse pregnancy outcomes.Nulliparous women in the first trimester of pregnancy were recruited into an observational cohort study. Participants were seen at 3 study visits during pregnancy and again at delivery. We collected data from in-clinic interviews, take-home surveys, clinical measurements, ultrasound studies, and chart abstractions. Maternal biospecimens (serum, plasma, urine, cervicovaginal fluid) at antepartum study visits and delivery specimens (placenta, umbilical cord, cord blood) were collected, processed, and stored. The primary outcome of the study was defined as pregnancy ending at37+0 weeks' gestation. Key study hypotheses involve adverse pregnancy outcomes of spontaneous preterm birth, preeclampsia, and fetal growth restriction.We recruited 10,037 women to the study. Basic characteristics of the cohort at screening are reported.The "Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be" cohort study methods and procedures can help investigators when they plan future projects.
- Subjects :
- Adult
Research design
medicine.medical_specialty
Adolescent
Umbilical cord
Article
Cohort Studies
Young Adult
Clinical Protocols
Pre-Eclampsia
Pregnancy
Risk Factors
medicine
Medicine and Health Sciences
Humans
Prospective Studies
Young adult
Prospective cohort study
Fetal Growth Retardation
Obstetrics
business.industry
Pregnancy Outcome
Obstetrics and Gynecology
medicine.disease
Parity
medicine.anatomical_structure
Research Design
Premature birth
Cohort
Premature Birth
Female
business
Cohort study
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Haas, David M; Parker, Corette B; Wing, Deborah A; Parry, Samuel; Grobman, William A; Mercer, Brian M; et al.(2015). A description of the methods of the Nulliparous Pregnancy Outcomes Study: monitoring mothers-to-be (nuMoM2b). American Journal of Obstetrics and Gynecology, 212(4), 539.e1-539.e24. doi: 10.1016/j.ajog.2015.01.019. UC Irvine: Institute for Clinical and Translational Science. Retrieved from: http://www.escholarship.org/uc/item/983198g6
- Accession number :
- edsair.doi.dedup.....a7f3c8dce5adfb069c8acc4de7006021