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Considerations for the treatment of pancreatic cancer during the COVID-19 pandemic: the UK consensus position
- Source :
- British Journal of Cancer
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Funder: DH | National Institute for Health Research (NIHR); doi: https://doi.org/10.13039/501100000272<br />Funder: Cancer Research UK (CRUK); doi: https://doi.org/10.13039/501100000289<br />The coronavirus disease 2019 (COVID-19) pandemic epicentre has moved to the USA and Europe, where it is placing unprecedented demands on healthcare resources and staff availability. These service constraints, coupled with concerns relating to an increased incidence and severity of COVID-19 among patients with cancer, should lead to re-consideration of the risk-benefit balance for standard treatment pathways. This is of particular importance to pancreatic cancer, given that standard diagnostic modalities such as endoscopy may be restricted, and that disease biology precludes significant delays in treatment. In light of this, we sought consensus from UK clinicians with an interest in pancreatic cancer for management approaches that would minimise patient risk and accommodate for healthcare service restrictions. The outcomes are described here and include recommendations for treatment prioritisation, strategies to bridge to later surgical resection in resectable disease and factors that modify the risk-benefit balance for treatment in the resectable through to the metastatic settings. Priority is given to strategies that limit hospital visits, including through the use of hypofractionated precision radiotherapy and chemoradiotherapy treatment approaches.
- Subjects :
- Risk
2019-20 coronavirus outbreak
Cancer Research
medicine.medical_specialty
Consensus
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Pneumonia, Viral
Disease
03 medical and health sciences
Betacoronavirus
0302 clinical medicine
Pancreatic cancer
Health care
Pandemic
Correspondence
medicine
Chemotherapy
Humans
030212 general & internal medicine
Intensive care medicine
Pandemics
Radiotherapy
business.industry
SARS-CoV-2
Standard treatment
Incidence (epidemiology)
Incidence
Consensus Statement
Cancer
COVID-19
medicine.disease
Virology
Health services
United Kingdom
Pancreatic Neoplasms
Position (obstetrics)
Oncology
030220 oncology & carcinogenesis
Practice Guidelines as Topic
Quarantine
business
Coronavirus Infections
Chemoradiotherapy
Subjects
Details
- ISSN :
- 00070920
- Database :
- OpenAIRE
- Journal :
- British Journal of Cancer
- Accession number :
- edsair.doi.dedup.....a7dedba5216251a0ec5407e5b98bcd41