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Clinical Characteristics of Cardioembolic Transient Ischemic Attack: Comparison with Noncardioembolic Transient Ischemic Attack

Clinical Characteristics of Cardioembolic Transient Ischemic Attack: Comparison with Noncardioembolic Transient Ischemic Attack

Authors :
Takeshi Hayashi
Yuito Nagamine
Yoshihide Sehara
Yohsuke Horiuchi
Norio Tanahashi
Yasuko Ohe
Ichiro Deguchi
Hajime Maruyama
Yuji Kato
Takuya Fukuoka
Hiroyasu Sano
Source :
Journal of Stroke and Cerebrovascular Diseases. 23:2169-2173
Publication Year :
2014
Publisher :
Elsevier BV, 2014.

Abstract

Background Previous studies show that 6%-31% of transient ischemic attacks (TIA) were caused by cardiogenic cerebral embolism (cardioembolic TIA). As prompt initiation of therapy is essential in TIA to prevent subsequent strokes, determining their cause is important. In this study, we aim to determine the features of cardioembolic TIA and to compare them with those of noncardioembolic etiology. Methods We retrospectively reviewed patients with a tissue-defined TIA who were admitted to our hospital from April 2007 to August 2013. The etiology was categorized according to Trial of Org 10172 in Acute Stroke Treatment, and TIA of cardioembolic origin and cervicocerebrovascular etiology (noncardioembolic TIA) were included in this study. Those with 2 or more possible causes or undetermined etiologies were excluded. Age, sex, comorbidities, ABCD2 score, and CHADS2 score were assessed and compared between the 2 groups. Results There were no significant differences in the neurologic symptoms and their duration, morbidities of hypertension, diabetes, and dyslipidemia between the 2 groups. Coronary and peripheral artery diseases were more common in the cardioembolic TIA group (18.4% vs. 6.9%). Incidences of prior stroke and cerebral infarction determined by MRI were similar between the 2 groups. The ABCD2 score showed a similar distribution, but the CHADS2 score was significantly different; the cardioembolic TIA group showed a higher score ( P = .005). Conclusions Clinical features are similar in tissue-defined TIA of cardioembolic and noncardioembolic etiologies. The CHADS2 score can be useful in assessing the probability of cardioembolic TIA.

Details

ISSN :
10523057
Volume :
23
Database :
OpenAIRE
Journal :
Journal of Stroke and Cerebrovascular Diseases
Accession number :
edsair.doi.dedup.....a7d602884603c0ca664b78ed7560b9f9
Full Text :
https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.04.005