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Factors influencing the local cure rate of hidradenitis suppurativa following wide local excision
- Source :
- Int Wound J
- Publication Year :
- 2019
- Publisher :
- Blackwell Publishing Ltd, 2019.
-
Abstract
- Wide local excision is the gold standard and only potential curative therapy for recalcitrant hidradenitis suppurativa. However, high recurrence rates persist even post-surgery with little known on the influencing factors for remission. We evaluated the effect of patient, disease, and operative factors on local cure rate of moderate to severe hidradenitis following wide local excision. We performed a retrospective chart review for all patients who had undergone surgical excision of hidradenitis at a university hospital from 2012 to 2018. We identified 79 patients with a total of 220 operative sites. The majority were obese (mean body mass index [BMI] 32.5), female (71%), African-American (84%), and had a mean age of 31 years. A quarter of operative sites experienced a recurrence (n = 56). Patients who achieved remission had a significantly lower number of affected regions than those who experienced a recurrence (2.3 vs 3.6, P = .0023). Additionally, recurrence rate differed significantly between body locations (P = .0440). Smoking, BMI, Hurley grade, closure method, and excision size did not influence local cure rate. Surgical excision remains a worthy management option for hidradenitis patients with three quarters achieving remission after a single operation. Number of affected regions and location of hidradenitis may play a factor in recurrence.
- Subjects :
- Moderate to severe
Adult
Male
medicine.medical_specialty
Cure rate
medicine.medical_treatment
Dermatology
030207 dermatology & venereal diseases
03 medical and health sciences
Young Adult
0302 clinical medicine
Recurrence
medicine
Humans
Hidradenitis suppurativa
030212 general & internal medicine
Retrospective Studies
Wound Healing
Maryland
business.industry
Wide local excision
Gold standard
Mean age
Original Articles
Skin Transplantation
medicine.disease
Hidradenitis
Surgery
Hidradenitis Suppurativa
Female
business
Body mass index
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Int Wound J
- Accession number :
- edsair.doi.dedup.....a7bfdb978865781e4ebe3b5647e24613