Heterogeneous somatic hypermutation status confounds the cell of origin in hairy cell leukemia

Authors :: Mia Thorsélius
Richard Rosenquist
Ulf Thunberg
Sarah H. Walsh
Hans Hagberg
Christer Sundström
Source :: Leukemia research. 29(2)
Publication Year :: 2004
Abstract: Hairy cell leukemia (HCL) is thought to arise from a post-germinal center (GC) B-cell, however the exact normal counterpart remains unclear. We performed VH gene analysis of 32 HCL cases, revealing somatically mutated VH genes (

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