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Bidirectional link between diabetes mellitus and coronavirus disease 2019 leading to cardiovascular disease: A narrative review
- Source :
- World Journal of Diabetes
- Publication Year :
- 2021
- Publisher :
- Baishideng Publishing Group Inc., 2021.
-
Abstract
- Coronavirus disease 2019 (COVID-19) is a global pandemic where several comorbidities have been shown to have a significant effect on mortality. Patients with diabetes mellitus (DM) have a higher mortality rate than non-DM patients if they get COVID-19. Recent studies have indicated that patients with a history of diabetes can increase the risk of severe acute respiratory syndrome coronavirus 2 infection. Additionally, patients without any history of diabetes can acquire new-onset DM when infected with COVID-19. Thus, there is a need to explore the bidirectional link between these two conditions, confirming the vicious loop between "DM/COVID-19". This narrative review presents (1) the bidirectional association between the DM and COVID-19, (2) the manifestations of the DM/COVID-19 loop leading to cardiovascular disease, (3) an understanding of primary and secondary factors that influence mortality due to the DM/COVID-19 loop, (4) the role of vitamin-D in DM patients during COVID-19, and finally, (5) the monitoring tools for tracking atherosclerosis burden in DM patients during COVID-19 and "COVID-triggered DM" patients. We conclude that the bidirectional nature of DM/COVID-19 causes acceleration towards cardiovascular events. Due to this alarming condition, early monitoring of atherosclerotic burden is required in "Diabetes patients during COVID-19" or "new-onset Diabetes triggered by COVID-19 in Non-Diabetes patients".
- Subjects :
- medicine.medical_specialty
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Endocrinology, Diabetes and Metabolism
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
030209 endocrinology & metabolism
Review
Disease
030204 cardiovascular system & hematology
03 medical and health sciences
Diabetes mellitus
0302 clinical medicine
Bidirectional association
Imaging tools
Internal medicine
Pandemic
Internal Medicine
medicine
business.industry
Mortality rate
COVID-19
Cardiovascular disease
medicine.disease
Atherosclerotic burden
Narrative review
business
Subjects
Details
- ISSN :
- 19489358
- Volume :
- 12
- Database :
- OpenAIRE
- Journal :
- World Journal of Diabetes
- Accession number :
- edsair.doi.dedup.....a784cb452aa89cc768c7e034be15ac44