Die Applikation von Adeno-assoziierten Viren Typ 2 (AAV-2) führt zur Tumorprotektion in einem syngenen Rattenmodell des Pankreaskarzinoms

The success of cancer gene therapy is likely to require the targeting of multiple antitumor mechanisms. In this study we demonstrate that infection of Lewis rats bearing pancreatic tumors with the Adenoassociated Virus type 2 (AAV-2) induces a systemic anti-tumor response and protects these animals from a subsequent tumor rechallenge.