Clinical Profile and Management Outcomes of Periocular Molluscum Contagiosum

Purpose: To study the clinical profile and management outcomes of histopathologically proven cases of eyelid molluscum contagiosum (MC). Materials and Methods: A retrospective analysis of the medical records of patients presenting to a tertiary eye care center between January 1995 and December 2018 was carried out. Of 67 patients clinically suspected of harboring molluscum lesions of the eyelids, 32 were confirmed on histopathology. Results: Mean age of the patients was 7 years (1.3–69). Of 32 patients, 17 (53%) were males and 15 (47%) were females. Eyelid mass lesion was the most common complaint (87.5%). Lower eyelid was the most common site (14/44%). Eighteen (56%) patients had a solitary lesion whereas 14 (44%) had multiple lesions. Characteristic umbilication was seen in 14 (44%) cases. Associated ocular surface findings were observed in 21 (66%) patients, of which most commonly noted were follicles, papillae, and eyelid edema. Lymphadenopathy was observed in two patients. Excision with or without cautery was performed in all patients. One patient had a recurrence after 5 months. None of the patients were immunocompromised. Most common misdiagnosis was sebaceous cyst (5), chalazia (2), and viral warts (2). A positive clinicopathological correlation was found in 59.34% cases. Conclusion: MC is a common infectious eyelid lesion in immunocompetent children. Characteristic central umbilication of the lesion provides a clue to clinical diagnosis; however, it can mimic many other eyelid lesions. Complete excision offers cure in almost all cases.