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Nonalcoholic Fatty Liver Disease and Advanced Fibrosis in US Adults Across Blood Pressure Categories
- Publication Year :
- 2020
- Publisher :
- Lippincott Williams and Wilkins, 2020.
-
Abstract
- Nonalcoholic fatty liver disease (NAFLD) is common in patients with hypertension but controversy exists as to whether screening for this condition should be performed. Here, we evaluate the prevalence of NAFLD and advanced fibrosis in US adults across blood pressure categories and estimate the number of patients who require referral to hepatologists. In this cross-sectional analysis of 11 489 adults from the 2005 to 2016 National Health and Nutrition Examination Survey, participants were segregated as having optimal, normal, high normal, and elevated blood pressure according to the 2018 European Society of Cardiology/Hypertension guidelines. NAFLD was defined using the US fatty liver index, whereas fibrosis was assessed using the NAFLD fibrosis score, fibrosis-4, and Hepamet Fibrosis Score. NAFLD prevalence increased progressively from optimal (16.5%) to normal (34.5%), high normal (39.9%), and elevated blood pressure (50.2%, P
- Subjects :
- Adult
Liver Cirrhosis
Male
medicine.medical_specialty
hypertension
National Health and Nutrition Examination Survey
Comorbidity
030204 cardiovascular system & hematology
03 medical and health sciences
0302 clinical medicine
Insulin resistance
Non-alcoholic Fatty Liver Disease
Fibrosis
Internal medicine
Diabetes mellitus
insulin resistance
Nonalcoholic fatty liver disease
Prevalence
Internal Medicine
medicine
Humans
Mass Screening
MED/13 - ENDOCRINOLOGIA
business.industry
Fatty liver
public health
nutritional and metabolic diseases
blood pressure
Middle Aged
Nutrition Surveys
medicine.disease
Cross-Sectional Studies
Blood pressure
Female
030211 gastroenterology & hepatology
Metabolic syndrome
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....a72bf2cf4a4620f8aa7278086c76840b