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Associations of life course socioeconomic position and job stress with carotid intima-media thickness. The Brazilian Longitudinal Study of Adult Health (ELSA-Brasil)
- Source :
- Repositório Institucional da UFOP, Universidade Federal de Ouro Preto (UFOP), instacron:UFOP, Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual), Universidade de São Paulo (USP), instacron:USP
- Publication Year :
- 2015
-
Abstract
- Rationale: The association between life course socioeconomic position (SEP) and subclinical atherosclerosis is not consistent across studies. Socioeconomic adversities early in life are related to an increased probability of a low occupational grade and more stressful jobs in adulthood. However, the role of job stress in explaining the life course social gradient in subclinical atherosclerosis is unknown. Objectives: To examine whether life course SEP is associated with carotid intima-media thickness (IMT) and to investigate whether this association is partially mediated by job stress. Methods: This study used baseline data (2008e2010) for 8806 current workers from ELSAeBrasil. Maternal education, social class of first occupation and social class of current occupation were used to evaluate childhood, youth and adulthood SEP, respectively. Accumulation of risk across the life course was also evaluated. Job stress was assessed by the Swedish DemandeControleSupport Questionnaire. Directed acyclic graph and linear regression models were used. Results: Low childhood SEP was associated with increased IMT only in women, but low youth and adulthood SEP were associated with higher IMT in both genders. The simultaneous adjustment for all SEP indicators showed that only adulthood SEP continued to be associated with IMT. However, higher IMT values were observed among men and women sequentially exposed to low SEP in more than one period of life. High-strain jobs and low job control were not associated with IMT independent of SEP. Conclusion: Our results support a model of the cumulative effects of exposures to SEP across the life span because the highest IMT values were observed in individuals sequentially exposed to low SEP in more than one period of life. We did not find that job stress explained the association between life course SEP and IMT, suggesting that strategies to address socioeconomic inequalities in CVD should target additional steps beyond reducing job stress.
- Subjects :
- Gerontology
Adult
Male
Longitudinal study
Aging
Health (social science)
Socioeconomic position
Carotid Artery, Common
Job control
Social class
Carotid Intima-Media Thickness
History and Philosophy of Science
Risk Factors
Surveys and Questionnaires
Medicine
Humans
Longitudinal Studies
Occupations
Socioeconomic status
Health inequalities
Aged
Job stress
business.industry
Life course
Middle Aged
Cardiovascular disease
Atherosclerosis
DOENÇAS CARDIOVASCULARES
Intima-media thickness
Social Class
Life course approach
Female
business
Brazil
Stress, Psychological
Subjects
Details
- ISSN :
- 18735347
- Volume :
- 141
- Database :
- OpenAIRE
- Journal :
- Social sciencemedicine (1982)
- Accession number :
- edsair.doi.dedup.....a6edbb756dff9384433ce0760d1ef202