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FOUR-YEAR FOLLOW-UP OF PREGNANCY-ASSOCIATED OSTEOPOROSIS: A CASE REPORT
- Source :
- FUKUSHIMA JOURNAL OF MEDICAL SCIENCE. 60:175-180
- Publication Year :
- 2014
- Publisher :
- The Fukushima Society of Medical Science, 2014.
-
Abstract
- A 22-year-old woman presented with complaints of severe pain in a wide region of the thoracolumbar spine. She developed severe pain in the thoracolumbar spine region 2 months after her first delivery and was referred 1 month later. A lateral thoracic X-ray showed depressed degenerative vertebrae (T7, T9). One month after the initial examination, thoracic sagittal magnetic resonance imaging showed low intensity areas on T1-weighted imaging and iso-high intensity areas on T2-weighted imaging at T5, 7, 8, 9 and 11. Bone mineral density measured by ultrasound was low (%YAM 76%). The bone metabolic markers were high, suggesting accelerated osteoclast activity. These findings prompted a diagnosis of pregnancy-associated osteoporosis. She was asked to stop breastfeeding and to wear a lumbar brace, and treatment with nutritional calcium, activated vitamin D3, and risedronate sodium was started. Her low back pain almost disappeared after treatment. Bone metabolic markers showed normalization 8 months after the initial examination. Risedronate sodium was stopped 2 years and 2 months after the initial examination. Teriparatide treatment was started because her bone mineral density remained low; however, the osteoblast marker P1NP was not increased 5 months after the start of teriparatide treatment.
- Subjects :
- musculoskeletal diseases
bisphosphonate
medicine.medical_specialty
medicine.medical_treatment
Osteoporosis
long-term follow-up
conservative treatment
Young Adult
Lumbar
Pregnancy
Teriparatide
Humans
Medicine
493.6
teriparatide
Bone mineral
Bone Density Conservation Agents
medicine.diagnostic_test
business.industry
Magnetic resonance imaging
General Medicine
Bisphosphonate
Pregnancy-associated osteoporosis
medicine.disease
Low back pain
Surgery
Pregnancy Complications
Risedronate Sodium
Female
medicine.symptom
business
Low Back Pain
Risedronic Acid
Follow-Up Studies
medicine.drug
Subjects
Details
- ISSN :
- 21854610 and 00162590
- Volume :
- 60
- Database :
- OpenAIRE
- Journal :
- FUKUSHIMA JOURNAL OF MEDICAL SCIENCE
- Accession number :
- edsair.doi.dedup.....a6cfe97712b892542954e4798477eabf