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Cow's milk protein β-lactoglobulin confers resilience against allergy by targeting complexed iron into immune cells
- Source :
- Digital.CSIC. Repositorio Institucional del CSIC, instname, Journal of Allergy and Clinical Immunology, 147(1), 321. Mosby Inc.
- Publication Year :
- 2021
-
Abstract
- Departamento de Biotecnología (INIA)<br />Beta-lactoglobulin (BLG) is a bovine lipocalin in milk with an innate defense function. The circumstances under which BLG is associated with tolerance of or allergy to milk are not understood.<br />Supported by the Austrian Science Fund FWF (grant SFB F4606-B28 ) and in part by Biomedical International R+D GmbH, Vienna, Austria, and by Bencard Allergie GmbH, Munich, Germany. S.M.A. was supported by a grant from the Egyptian Ministry of Higher Education .<br />18 Pág.
- Subjects :
- 0301 basic medicine
Allergy
Milk allergy
Lipocalin
Lactoglobulins
Immunoglobulin E
ligand
quercetin
Allergic sensitization
Mice
0302 clinical medicine
iron
Immunology and Allergy
Mast Cells
Cow's milk
Mice, Inbred BALB C
milk
tolerance
biology
Chemistry
Allergen
Degranulation
Mast cell
BLG
Interleukin 10
medicine.anatomical_structure
Milk
Quercetin
lipocalin
Iron
Antigen presentation
Immunology
Ligand
β-lactoglobulin
03 medical and health sciences
Immune system
medicine
Animals
Humans
medicine.disease
allergy
Bos d 5
cow's milk
030104 developmental biology
030228 respiratory system
biology.protein
Leukocytes, Mononuclear
Cattle
Milk Hypersensitivity
Tolerance
Subjects
Details
- Language :
- English
- ISSN :
- 00916749
- Volume :
- 147
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Journal of Allergy and Clinical Immunology
- Accession number :
- edsair.doi.dedup.....a6c2ba08b28141a6c9a477c8e71d9e6f