An analysis of MRI derived cortical complexity in premature-born adults: Regional patterns, risk factors, and potential significance

Premature birth bears an increased risk for aberrant brain development concerning its structure and function. Cortical complexity (CC) expresses the fractal dimension of the brain surface and changes during neurodevelopment. We hypothesized that CC is altered after premature birth and associated with long-term cognitive development.\ud \ud One-hundred-and-one very premature-born adults (gestational age