Design and Synthesis of Novel Conformationally Restricted Peptide Secondary Structure Mimetics

Authors :: Hwa-Ok Kim
Hiroshi Nakanishi
Michael G. Kahn
Min S. Lee,†,‡ and
Source :: Organic Letters. 2:301-302
Publication Year :: 2000
Publisher :: American Chemical Society (ACS), 2000.
Abstract: [structure: see text] A facile synthesis of the novel conformationally restricted reverse turn mimetic is described. The key features are the preparation of the alpha-keto amide and tandem bicyclic ring formation.

Subjects :: chemistry.chemical_classification
Bicyclic molecule
Tandem
Stereochemistry
Organic Chemistry
Peptide
Key features
Ring (chemistry)
Biochemistry
Turn (biochemistry)
chemistry.chemical_compound
chemistry
Amide
Physical and Theoretical Chemistry
Protein secondary structure

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