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An unusual case of Plasmodium vivax malaria monoinfection associated with crescentic glomerulonephritis: a need for vigilance
- Source :
- Parasitology Research. 112:427-430
- Publication Year :
- 2012
- Publisher :
- Springer Science and Business Media LLC, 2012.
-
Abstract
- Plasmodium vivax infection is increasingly a major public health burden and the second most frequent human malaria. Higher levels of clinical severity and chloroquine resistance are major factors responsible for such increases. Malarial glomerular injury is uncommon and mainly observed in Plasmodium malariae-infected patients. Occasionally, transient immune complex-mediated glomerulonephritis is associated with Plasmodium falciparum infection. Coexistent crescentic glomerulonephritis and vivax malaria have not previously been reported. We report a fatal case of P. vivax malaria, who presented with acute renal failure. P. vivax monoinfection status was diagnosed with peripheral blood smear and rapid antigen test. Further evaluation for renal failure related to systemic illness and immunological markers were inconclusive. He was treated with antimalarial drugs, hemodialysis, and supportive therapy. Renal biopsy performed for nonrecovering renal failure reveled crescentic glomerulonephritis. This case highlights the need to thoroughly search for malaria-associated crescentic glomerulonephritis using renal biopsy after nonrecovering renal failure.
- Subjects :
- Male
medicine.medical_specialty
Adolescent
Biopsy
medicine.medical_treatment
urologic and male genital diseases
Antimalarials
chemistry.chemical_compound
Fatal Outcome
Glomerulonephritis
Medical microbiology
Immune system
parasitic diseases
Malaria, Vivax
medicine
Humans
Renal Insufficiency
General Veterinary
medicine.diagnostic_test
business.industry
General Medicine
medicine.disease
Infectious Diseases
chemistry
Artesunate
Insect Science
Immunology
Parasitology
Renal biopsy
Hemodialysis
Plasmodium vivax
business
Malaria
Subjects
Details
- ISSN :
- 14321955 and 09320113
- Volume :
- 112
- Database :
- OpenAIRE
- Journal :
- Parasitology Research
- Accession number :
- edsair.doi.dedup.....a67c3711d3d740c5a81adac55b148003