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Sex differences in implantable cardioverter-defibrillator implantation indications and outcomes: lessons from the Nationwide Israeli-ICD Registry
- Source :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 16(8)
- Publication Year :
- 2014
-
Abstract
- Aims Implantable cardioverter-defibrillators (ICDs) improve survival in certain high arrhythmic risk populations. However, there are sex differences regarding both the utilization and the benefit of these devices. Using a prospective national ICD registry, we aim to compare the indications for ICD implantation as well as outcomes in implanted women vs. men. Methods and results All subjects implanted with an ICD or cardiac resynchronization therapy with a defibrillator (CRTD) in Israel between July 2010 and February 2013 were included. A total of 3544 subjects constructed the baseline cohort, of whom 615 (17%) were women. Women had the same age (64 years) and rate of secondary prevention indication (26%) as men. However, women were more likely than men to have significant heart failure symptoms (52 vs. 45%), QRS > 120 ms (41 vs. 36%), and a higher rate of non-ischaemic cardiomyopathy (54 vs. 21%, all P values
- Subjects :
- Male
medicine.medical_specialty
Multivariate analysis
Time Factors
medicine.medical_treatment
Cardiomyopathy
Cardiac resynchronization therapy
Electric Countershock
Kaplan-Meier Estimate
Cardiac Resynchronization Therapy
QRS complex
Sex Factors
Risk Factors
Physiology (medical)
Internal medicine
medicine
Odds Ratio
Secondary Prevention
Humans
Cardiac Resynchronization Therapy Devices
Prospective Studies
Registries
Healthcare Disparities
Israel
Aged
Proportional Hazards Models
Heart Failure
Chi-Square Distribution
business.industry
Arrhythmias, Cardiac
Odds ratio
Health Status Disparities
Middle Aged
medicine.disease
Implantable cardioverter-defibrillator
Surgery
Defibrillators, Implantable
Hospitalization
Primary Prevention
Death, Sudden, Cardiac
Logistic Models
Treatment Outcome
Heart failure
Cohort
Multivariate Analysis
Retreatment
Female
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 15322092
- Volume :
- 16
- Issue :
- 8
- Database :
- OpenAIRE
- Journal :
- Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology
- Accession number :
- edsair.doi.dedup.....a66eb40c510fca40de02e66f2aff1369