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Properties of liposomes with a phospholipid ratio similar to that of retinal rod outer segment membranes: Interaction with opsin and other proteins
- Source :
- Experimental Eye Research. 24:279-289
- Publication Year :
- 1977
- Publisher :
- Elsevier BV, 1977.
-
Abstract
- Liposomes have been prepared with a phospholipid ratio and a cholesterol content similar to that of the outer segments of rod photoreceptor cells. Studies were made of the appearance, electrophoretic mobility and sodium leakage rates of the liposomes, with and without the inclusion of protein (albumin, myoglobin, ribonuclease, lysozyme, proteolipid or opsin). The findings indicate that although the appearance and properties of these liposomes closely resemble those of other liposomes reported in the literature, the liposomes become markedly changed in appearance, electrophoretic mobility and sodium permeability by the addition of opsin. These data emphasize the hydrophobic nature of the opsin-lipid interaction and suggest an ability of opsin to alter the ion leakage properties of a rod outer segment membrane.
- Subjects :
- Opsin
Cell Membrane Permeability
genetic structures
Sodium
chemistry.chemical_element
Biology
Membrane Lipids
Cellular and Molecular Neuroscience
chemistry.chemical_compound
Microelectrophoresis
Photoreceptor Cells
Eye Proteins
Phospholipids
Liposome
Membrane Proteins
Biological Transport
Retinal
eye diseases
Sensory Systems
Ophthalmology
Membrane
chemistry
Myoglobin
Biochemistry
Liposomes
sense organs
Lysozyme
Retinal Pigments
Subjects
Details
- ISSN :
- 00144835
- Volume :
- 24
- Database :
- OpenAIRE
- Journal :
- Experimental Eye Research
- Accession number :
- edsair.doi.dedup.....a66dc2b4cba1620efb33223bd7b8abae