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The prognostic value of the pretreatment serum albumin to globulin ratio for predicting adverse pathology in patients undergoing radical prostatectomy for prostate cancer
- Source :
- Investigative and Clinical Urology, Investigative and Clinical Urology, Vol 62, Iss 5, Pp 545-552 (2021)
- Publication Year :
- 2021
- Publisher :
- The Korean Urological Association, 2021.
-
Abstract
- Purpose: Few studies have demonstrated the clinical significance of pretreatment serum albumin and globulin in prostate cancer (PCa). This study evaluated the association between the pretreatment albumin to globulin ratio (AGR) and clinicopathologic characteristics of nonmetastatic PCa in a large multicenter setting in Korea. Materials and Methods: This study involved 742 patients with nonmetastatic PCa who underwent radical prostatectomy (RP) in seven institutions between January 2011 and December 2012. The AGR was calculated as follows: albumin/(total protein−albumin). Patients were divided into low and high AGR groups by a cutoff value from a receiver operating characteristic curve analysis. Results: The best cutoff for the AGR was set at 1.53. The area under the curve of the AGR was 0.624 (95% confidence interval, 0.557–0.671; p
- Subjects :
- Male
Pathology
medicine.medical_specialty
Globulin
Urological Oncology
Urology
medicine.medical_treatment
Serum albumin
Prostate cancer
Postoperative Complications
Predictive Value of Tests
medicine
Humans
Clinical significance
Serum Albumin
Aged
Retrospective Studies
Prostatectomy
biology
business.industry
Albumin
Area under the curve
Prostatic Neoplasms
biochemical phenomena, metabolism, and nutrition
Middle Aged
medicine.disease
bacterial infections and mycoses
Prognosis
Confidence interval
Diseases of the genitourinary system. Urology
Preoperative Period
biology.protein
bacteria
Original Article
Serum Globulins
RC870-923
business
Subjects
Details
- Language :
- English
- ISSN :
- 2466054X and 24660493
- Volume :
- 62
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Investigative and Clinical Urology
- Accession number :
- edsair.doi.dedup.....a63873513b30df65cf0d372ae001f7e2