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Association of vitamin D receptor gene TaqI polymorphism with Alzheimer's disease in a Southeastern European Caucasian population

Authors :
Efthimios Dimitrakis
Martha-Spyridoula Katsarou
Maria Lagiou
Vasiliki Papastefanopoulou
Evangelia Stanitsa
Demetrios Spandidos
Aristidis Tsatsakis
Socratis Papageorgiou
Paraskevi Moutsatsou
Katerina Antoniou
Christos Kroupis
Nikolaos Drakoulis
Source :
Experimental and therapeutic medicine. 23(5)
Publication Year :
2022

Abstract

The role of vitamin D in Alzheimer's Disease (AD) has been studied over the past years. The results from numerous studies have indicated that the molecular pathways involved in the development of AD are closely related to the molecular pathways of the mechanisms of action of vitamin D. However, only a limited number of studies have described the key role of vitamin D receptor (VDR) in the regulation of the functions of vitamin D and the potential effect of single nucleotide polymorphisms (SNPs) of the

Details

ISSN :
17921015
Volume :
23
Issue :
5
Database :
OpenAIRE
Journal :
Experimental and therapeutic medicine
Accession number :
edsair.doi.dedup.....a617a480d9f8d92410c6cc79c52a52b5