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The 3' noncoding region of beta-globin mRNA is not essential for in vitro translation
- Source :
- Nucleic acids research. 6(1)
- Publication Year :
- 1979
-
Abstract
- Rabbit beta globin DNA sequence, excised from plasmid pbetaG1, directs in vitro synthesis of beta-globin in a transcription-translation cell-free system, even after specific elimination of the entire 3'-noncoding region. A DNA restriction fragment carrying this 3' noncoding region and hybridized to globin mRNA cannot arrest the cell-free translation of beta-globin mRNA.
- Subjects :
- Reticulocytes
Transcription, Genetic
Biology
Restriction fragment
chemistry.chemical_compound
Plasmid
Polysome
hemic and lymphatic diseases
Genetics
Protein biosynthesis
Animals
Globin
RNA, Messenger
Messenger RNA
Translation (biology)
Molecular biology
Globins
Kinetics
chemistry
Polyribosomes
Protein Biosynthesis
biology.protein
Rabbits
DNA
Plasmids
Research Article
Subjects
Details
- ISSN :
- 03051048
- Volume :
- 6
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Nucleic acids research
- Accession number :
- edsair.doi.dedup.....a5f874c21a02be15b823ec018dd38b0a