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Multinational outbreak of travel-related Salmonella Chester infections in Europe, summers 2014 and 2015

Authors :
Céline M Gossner
Carmen Varela Martinez
Ettore Severi
Ingrid H M Friesema
Kathie Grant
Philip Ashton
Abdellah El Boulani
Nathalie Jourdan-Da Silva
Wesley Mattheus
Luise Müller
Brahim Bouchrif
Laure Fonteneau
Simon Le Hello
François-Xavier Weill
Mia Torpdahl
Joël Mossong
Eleni Valkanou
Silvia Leon
Laetitia Fabre
Timothy J. Dallman
Sophie Bertrand
Santé publique France - French National Public Health Agency [Saint-Maurice, France]
European Centre for Disease Prevention and Control (ECDC)
Centre National de Référence - National Reference Center Escherichia coli, Shigella et Salmonella (CNR-ESS)
Institut Pasteur [Paris]
Statens Serum Institut [Copenhagen]
Université Ibn Zohr [Agadir]
NRL Salmonella & AMR
Veterinary Laboratory of Chalkida
Institut Scientifique de Santé Publique [Belgique] - Scientific Institute of Public Health [Belgium] (WIV-ISP)
Réseau International des Instituts Pasteur (RIIP)
National Institute for Public Health and the Environment [Bilthoven] (RIVM)
Instituto de Salud Carlos III [Madrid] (ISC)
Laboratoire National de Santé [Luxembourg] (LNS)
European Centre for Disease Prevention and Control [Stockholm, Sweden] (ECDC)
Institut Pasteur [Paris] (IP)
Source :
Eurosurveillance, Eurosurveillance, European Centre for Disease Prevention and Control, 2017, 22 (7), ⟨10.2807/1560-7917.ES.2017.22.7.30463⟩, Repisalud, Instituto de Salud Carlos III (ISCIII), Eurosurveillance, 2017, 22 (7), ⟨10.2807/1560-7917.ES.2017.22.7.30463⟩
Publication Year :
2017

Abstract

Between 2014 and 2015, the European Centre for Disease Prevention and Control was informed of an increase in numbers of Salmonella enterica serotype Chester cases with travel to Morocco occurring in six European countries. Epidemiological and microbiological investigations were conducted. In addition to gathering information on the characteristics of cases from the different countries in 2014, the epidemiological investigation comprised a matched case–case study involving French patients with salmonellosis who travelled to Morocco that year. A univariate conditional logistic regression was performed to quantify associations. The microbiological study included a whole genome sequencing (WGS) analysis of clinical and non-human isolates of S. Chester of varied place and year of isolation. A total of 162 cases, mostly from France, followed by Belgium, the Netherlands, Spain, Denmark and Sweden were reported, including 86 (53%) women. The median age per country ranged from 3 to 38 years. Cases of S. Chester were more likely to have eaten in a restaurant and visited the coast of Morocco. The results of WGS showed five multilocus sequence types (ST), with 96 of 153 isolates analysed clustering into a tight group that corresponded to a novel ST, ST1954. Of these 96 isolates, 46 (48%) were derived from food or patients returning from Morocco and carried two types of plasmids containing either qnrS1 or qnrB19 genes. This European-wide outbreak associated with travel to Morocco was likely a multi-source outbreak with several food vehicles contaminated by multidrug-resistant S. Chester strains.

Details

Language :
English
ISSN :
15607917 and 1025496X
Volume :
22
Issue :
7
Database :
OpenAIRE
Journal :
Eurosurveillance
Accession number :
edsair.doi.dedup.....a5f240d808de7b52ce389d1268abccea
Full Text :
https://doi.org/10.2807/1560-7917.ES.2017.22.7.30463⟩