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Large Visual Stimuli Induce Two Distinct Gamma Oscillations in Primate Visual Cortex
- Source :
- The Journal of Neuroscience
- Publication Year :
- 2018
- Publisher :
- Society for Neuroscience, 2018.
-
Abstract
- Recent studies have shown the existence of two gamma rhythms in the hippocampus subserving different functions but, to date, primate studies in primary visual cortex have reported a single gamma rhythm. Here, we show that large visual stimuli induce a slow gamma (25–45 Hz) in area V1 of two awake adult female bonnet monkeys and in the EEG of 15 human subjects (7 males and 8 females), in addition to the traditionally known fast gamma (45–70 Hz). The two rhythms had different tuning characteristics for stimulus orientation, contrast, drift speed, and size. Further, fast gamma had short latency, strongly entrained spikes and was coherent over short distances, reflecting short-range processing, whereas slow gamma appeared to reflect long-range processing. Together, two gamma rhythms can potentially provide better coding or communication mechanisms and a more comprehensive biomarker for diagnosis of mental disorders.SIGNIFICANCE STATEMENTGamma rhythm has been associated with high-level cognitive functions such as attention and feature binding and has been reported to be abnormal in brain disorders such as autism and schizophrenia. Unlike previous studies that have shown a single gamma rhythm in the primate visual cortex, we found that large visual gratings induce two distinct gamma oscillations in both monkey LFP and human EEG. These rhythms, termed slow (25–45 Hz) and fast (45–70 Hz), exhibited distinct tuning preferences, latencies, and coherence profiles, potentially reflecting processing at two different ranges. Multiple gamma oscillations in visual cortex may provide a richer representation of external visual stimuli and could be used for developing brain–machine interfacing applications and screening tests for neuropsychiatric disorders.
- Subjects :
- Male
0301 basic medicine
Visual perception
LFP
Fixation, Ocular
Stimulus (physiology)
Electroencephalography
rhythm
Young Adult
03 medical and health sciences
0302 clinical medicine
Rhythm
Systems/Circuits
biology.animal
Gamma Rhythm
medicine
Animals
Humans
Primate
EEG
Research Articles
Visual Cortex
biology
medicine.diagnostic_test
General Neuroscience
Cognition
oscillation
Macaca radiata
030104 developmental biology
Visual cortex
medicine.anatomical_structure
area V1
Evoked Potentials, Visual
gamma
Female
Neuroscience
Algorithms
Photic Stimulation
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 15292401 and 02706474
- Volume :
- 38
- Database :
- OpenAIRE
- Journal :
- The Journal of Neuroscience
- Accession number :
- edsair.doi.dedup.....a592d6cb830ca23d17ff00137f6051e8