2313. Risk of Relapsed or Persistent Infection Caused by Enterobacter Species in Children

Background Enterobacter species are a major cause of infections in hospitalized children. Treatment is complicated by the presence of a chromosomal AmpC β-lactamase, capable of inactivating certain antibiotics, including third-generation cephalosporins (3GC). Previous studies in adults have reported a 3–19% risk of relapsed bacteremia with 3GC therapy. Data in children regarding risk factors predicting relapse or persistence of infection are lacking. We sought to determine the frequency of and risk factors for relapse or persistence of Enterobacter infection in children. Methods Retrospective study of patients