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Arterial hypertension – Clinical trials update 2021
- Source :
- Nutrition, Metabolism, and Cardiovascular Diseases
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Aim This review aims to summarize and discuss some of the most relevant clinical trials in epidemiology, diagnostics, and treatment of hypertension published in 2020 and 2021. Data synthesis The trials included in this review are related to hypertension onset age and risk for future cardiovascular disease, reliability of different blood pressure monitoring methods, role of exercise-induced hypertension, treatment of hypertension in patients with SARS-CoV-2 infection, management of hypertension high-risk patient groups, e.g., in the elderly (≥80 years) and patients with atrial fibrillation, and the interplay between nutrition and hypertension, as well as recent insights into renal denervation for treatment of hypertension. Conclusions Hypertension onset age, nighttime blood pressure levels and a riser pattern are relevant for the prognosis of future cardiovascular diseases. The risk of coronary heart disease appears to increase linearly with increasing exercise systolic blood pressure. Renin-angiotensin system blockers are not associated with an increased risk for a severe course of COVID-19. In elderly patients, a risk-benefit assessment of intensified blood pressure control should be individually evaluated. A J-shaped association between cardiovascular disease and achieved blood pressure could also be demonstrated in patients with atrial fibrillation on anticoagulation. Salt restriction and lifestyle modification remain effective options in treating hypertensive patients at low cardiovascular risk. Sodium glucose co-transporter 2 inhibitors and Glucagon-like peptide-1 receptor agonists show BP-lowering effects. Renal denervation should be considered as an additional or alternative treatment option in selected patients with uncontrolled hypertension.
- Subjects :
- Arterial hypertension
cardiovascular risk
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Endocrinology, Diabetes and Metabolism
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Medicine (miscellaneous)
Review
Disease
exercise-induced hypertension
Internal medicine
Epidemiology
Humans
Medicine
renal denervation
Denervation
Clinical Trials as Topic
Nutrition and Dietetics
business.industry
COVID-19
Atrial fibrillation
medicine.disease
Clinical trial
Blood pressure
Hypertension
Cardiology
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- ISSN :
- 09394753
- Volume :
- 32
- Database :
- OpenAIRE
- Journal :
- Nutrition, Metabolism and Cardiovascular Diseases
- Accession number :
- edsair.doi.dedup.....a548d3f07b81dc12d3f7ab75a7ca2201