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The Influence of Different Classes of Amino Acids on Calcium Phosphates Seeded Growth
- Source :
- Materials, Volume 13, Issue 21, Materials, Vol 13, Iss 4798, p 4798 (2020)
- Publication Year :
- 2020
- Publisher :
- Multidisciplinary Digital Publishing Institute, 2020.
-
Abstract
- Amino acids (AAs) attract attention for elucidating the role of proteins in biomineralization and the preparation of functionalized biomaterials. The influence that AAs exert on calcium phosphate (CaP) mineralization is still not completely understood, as contradictory results have been reported. In this paper, the influence of the addition of different classes of AAs, charged (L-aspartic acid, Asp<br />L-lysine, Lys), polar (L-asparagine, Asn<br />L-serine, Ser<br />L-tyrosine, Tyr), and non-polar (L-phenylalanine, Phe), on CaP growth in the presence of octacalcium phosphate (OCP) and calcium hydrogenphosphate dihydrate (DCPD) seeds was investigated. In control systems (without AAs), a calcium-deficient apatite (CaDHA) layer was formed on the surface of OCP, while a mixture of CaDHA and OCP in the form of spherical aggregates was formed on the surface of DCPD crystals. Charged and non-polar promoted, while polar AAs inhibited CaDHA formation on the OCP seeds. In the case of DCPD, Lys, Asp, and Phe promoted CaP formation, while the influence of other AAs was negligible. The most efficient promotor of precipitation in both cases was non-polar Phe. No significant influence of AAs on the composition and morphology of precipitates was observed. The obtained results are of interest for understanding biomineralization processes and additive controlled material synthesis.
- Subjects :
- chemistry.chemical_element
octacalcium phosphate
02 engineering and technology
Calcium
010402 general chemistry
01 natural sciences
Mineralization (biology)
lcsh:Technology
Article
Apatite
dicalcium hydrogenphosphate dihydrate
amino acids
biomineralization
seeded growth
chemistry.chemical_compound
General Materials Science
Cap formation
Octacalcium phosphate
lcsh:Microscopy
lcsh:QC120-168.85
chemistry.chemical_classification
lcsh:QH201-278.5
Precipitation (chemistry)
lcsh:T
021001 nanoscience & nanotechnology
0104 chemical sciences
Amino acid
Chemistry
chemistry
lcsh:TA1-2040
visual_art
visual_art.visual_art_medium
lcsh:Descriptive and experimental mechanics
lcsh:Electrical engineering. Electronics. Nuclear engineering
0210 nano-technology
lcsh:Engineering (General). Civil engineering (General)
lcsh:TK1-9971
Nuclear chemistry
Biomineralization
Subjects
Details
- Language :
- English
- ISSN :
- 19961944
- Database :
- OpenAIRE
- Journal :
- Materials
- Accession number :
- edsair.doi.dedup.....a4ff13b05cdfb3aa733e5dd3b7b2e4cc
- Full Text :
- https://doi.org/10.3390/ma13214798