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Diketopiperazines, inhibitors of sterol O-acyltransferase, produced by a marine-derived Nocardiopsis sp. KM2-16
- Source :
- The Journal of Antibiotics. 68:638-641
- Publication Year :
- 2015
- Publisher :
- Springer Science and Business Media LLC, 2015.
-
Abstract
- Diketopiperazines, inhibitors of sterol O -acyltransferase, produced by a marine-derived Nocardiopsis sp. KM2-16
- Subjects :
- Stereochemistry
Sterol O-acyltransferase
Molecular Conformation
Tetrazolium Salts
CHO Cells
Diketopiperazines
Endoplasmic Reticulum
chemistry.chemical_compound
Cricetulus
Cricetinae
Actinomycetales
Drug Discovery
polycyclic compounds
Animals
Enzyme Inhibitors
Pharmacology
biology
Chinese hamster ovary cell
biology.organism_classification
Nocardiopsis sp
Sterol
Thiazoles
Biochemistry
chemistry
Acyltransferase
lipids (amino acids, peptides, and proteins)
Formazan
Sterol O-Acyltransferase
Subjects
Details
- ISSN :
- 18811469 and 00218820
- Volume :
- 68
- Database :
- OpenAIRE
- Journal :
- The Journal of Antibiotics
- Accession number :
- edsair.doi.dedup.....a4d8b5bad7c5c42d21bdeaa7c0865f1e
- Full Text :
- https://doi.org/10.1038/ja.2015.38