Back to Search
Start Over
Planned preservation surgery for soft tissue sarcomas adjacent to critical structures
- Source :
- Archives of orthopaedic and trauma surgery. 133(4)
- Publication Year :
- 2012
-
Abstract
- Whether to preserve or sacrifice critical structures (bone, major vessels and major nerves) adjacent to soft tissue sarcomas is still controversial. Referring to characteristic imaging and intraoperative findings, we perform planned preservation surgery for these critical structures. The aim of this study was to investigate the clinical outcome of soft tissue sarcomas adjacent to critical structures and to validate this procedure.Of 202 cases of soft tissue sarcomas surgically treated at our department of orthopedic surgery from 2004 to 2010, 57 cases (28 %) whose tumors were adjacent to the critical structures were studied. There were 36 men and 21 women. In 32 cases critical structures were preserved, and in 25 resected together with the tumor. The oncological outcome and histological surgical margin were analyzed.The overall survival and local recurrence-free survival rates at 5 years were 75.9 and 83.2 %. In 26 of the 32 (81 %) preserved cases histologically the surgical margin was negative, and in 17 (53 %) radiotherapy could be avoided. Neither overall survival (p = 0.9669) nor local recurrence-free survival (p = 0.7819) differed significantly between two groups.When soft tissue sarcomas are located adjacent to bone or major vessels, by meticulously detaching the periosteum or neurovascular sheath referring to characteristic imaging and intraoperative findings, a histologically negative surgical margin can be achieved in the majority, allowing avoidance of postoperative radiotherapy. Planned preservation surgery provided no significant adverse effect on survival or local recurrence rates, validating this procedure.
- Subjects :
- Adult
Male
medicine.medical_specialty
Surgical margin
Soft Tissue Neoplasm
Adolescent
Limb salvage
Soft Tissue Neoplasms
Bone and Bones
Young Adult
medicine
Humans
Orthopedics and Sports Medicine
Peripheral Nerves
Child
Aged
Aged, 80 and over
Critical structure
business.industry
Soft tissue sarcoma
Soft tissue
Sarcoma
General Medicine
Middle Aged
medicine.disease
Survival Analysis
Surgery
Child, Preschool
Orthopedic surgery
Blood Vessels
Female
business
Vascular Surgical Procedures
Subjects
Details
- ISSN :
- 14343916
- Volume :
- 133
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Archives of orthopaedic and trauma surgery
- Accession number :
- edsair.doi.dedup.....a44ff422c7618a649129e7e9f2142273