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Posttransplantation cyclophosphamide and sirolimus for prevention of GVHD after HLA-matched PBSC transplantation
- Publication Year :
- 2016
-
Abstract
- To the editor: Graft-versus-host disease (GVHD), both acute and chronic, is still a leading cause of nonrelapse mortality after transplantation.[1][1] High-dose, posttransplantation cyclophosphamide (PTCy) is an attractive approach for in vivo allodepletion across the HLA barrier in allogeneic
- Subjects :
- Oncology
Adult
Male
medicine.medical_specialty
Transplantation Conditioning
Cyclophosphamide
Immunology
Graft vs Host Disease
PBSC transplantation
Human leukocyte antigen
Disease
Biochemistry
Chemoprevention
03 medical and health sciences
0302 clinical medicine
immune system diseases
In vivo
Internal medicine
Medicine
Humans
Nonrelapse mortality
Aged
Sirolimus
Peripheral Blood Stem Cell Transplantation
business.industry
Histocompatibility Testing
Cell Biology
Hematology
Middle Aged
surgical procedures, operative
030220 oncology & carcinogenesis
Hematologic Neoplasms
Female
business
030215 immunology
medicine.drug
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....a39cdb1c54c997497020e541e7b91c67