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Emergence of the brain-stem auditory evoked potential in the premature lamb
- Source :
- Electroencephalography and clinical neurophysiology. 75(3)
- Publication Year :
- 1990
-
Abstract
- Brain-stem auditory evoked potentials (BAEPs) were elicited by bone conducted stimuli in the very immature lamb following delivery, wherein liquid ventilation techniques were utilized to control cardiopulmonary and acid-base conditions, independent of umbilical-placenta support. Unlike previous studies of the in utero fetal lamb in which the BAEP could not be elicited by earphone delivered stimuli until 117 days gestation, our results demonstrate that the BAEP emerges at least as early as 106 days gestation in the lamb and consists of a full complement of readily discernible and reproducible wave forms. In addition, the results demonstrate substantial maturation of the BAEP from 106 to 122 days gestation during which time there is a significant decrease in absolute and interpeak latencies with an increase in developmental age. It is concluded that the ability to elicit the BAEP utilizing bone conduction at this early stage of gestation is related to improved stimuli delivery. Furthermore, this study demonstrates the feasibility and flexibility afforded by liquid ventilation and bone conduction BAEP techniques to study brain-stem function at particularly vulnerable stages of development.
- Subjects :
- medicine.medical_specialty
Sheep
genetic structures
business.industry
General Neuroscience
Gestational age
Gestational Age
Audiology
Bone conduction
Animals, Newborn
In utero
Fetal lamb
medicine
Evoked Potentials, Auditory
Gestation
Animals
Regression Analysis
Liquid ventilation
Neurology (clinical)
Evoked potential
Auditory Physiology
business
Bone Conduction
Brain Stem
Subjects
Details
- ISSN :
- 00134694
- Volume :
- 75
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Electroencephalography and clinical neurophysiology
- Accession number :
- edsair.doi.dedup.....a39bba58c934104c397a33d4496f8c4a