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Administering analgesia sublingually is a suitable option for children with acute abdominal pain in the emergency department
- Publication Year :
- 2019
-
Abstract
- Aim Acute abdominal pain is a frequent complaint in children attending emergency departments. The aim of this study was to investigate the pain score reductions when children with acute abdominal pain received medication sublingually. Methods We carried out a multicentre randomised controlled trial in three children's hospitals in Italy between March 2015 and June 2017. Children from four to 18 years of age with acute abdominal pain were recruited if their self-reported pain was at least six on a scale from 0-10. The children were randomised to receive ketorolac 0.5 mg/kg (n = 70) or tramadol 2 mg/kg (n = 70) sublingually or a melt in the mouth powder of 20 mg/kg paracetamol (n = 70). The main study outcome was the pain scores for the three drugs after two hours. Results The 210 children (58.6% girls) had a median age of 12 years with an interquartile range of 9-14.3. The median pain scores at two hours were not significantly different between ketorolac 2.0 (interquartile ranges, IQR 0.0-4.3) and tramadol 3.0 (IQR 1.0-5.0) vs paracetamol 3.0 (IQR 0.8-5.0). The median pain reductions were all 5.0 points. Conclusion Delivering analgesia sublingually was a suitable option for pain relief in children with acute abdominal pain in the emergency department.
- Subjects :
- Male
Acute abdominal pain
Pediatrics
law.invention
0302 clinical medicine
Randomized controlled trial
law
Interquartile range
Medicine
030212 general & internal medicine
Child
Children
Tramadol
Pain Measurement
Analgesia
Emergency department
Sublingual
Pediatrics, Perinatology and Child Health
Anti-Inflammatory Agents, Non-Steroidal
General Medicine
Analgesics, Non-Narcotic
Perinatology and Child Health
Hospitals, Pediatric
Treatment Outcome
Italy
Settore MED/38 - PEDIATRIA GENERALE E SPECIALISTICA
Child, Preschool
Anesthesia
Acute Disease
Female
Emergency Service, Hospital
medicine.drug
Adolescent
Administration, Sublingual
Statistics, Nonparametric
03 medical and health sciences
030225 pediatrics
Humans
Administering analgesia
Acetaminophen
Pain score
business.industry
Abdominal Pain
Ketorolac
Logistic Models
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Accession number :
- edsair.doi.dedup.....a3647f82ab1c22cced2faa1b06f53dc0