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Strain pattern and T-wave alterations are predictors of mortality and poor neurologic outcome following stroke
- Source :
- Scopus, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP, Clinical Cardiology
- Publication Year :
- 2020
-
Abstract
- Made available in DSpace on 2020-12-12T02:11:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-06-01 Background: Stroke is associated with electrocardiogram (ECG) abnormalities. However, the role of strain pattern as predictor of poor neurologic outcome and mortality after stroke has not yet been demonstrated. Hypothesis: ECG abnormalities, with a particular focus on ST-segment changes, are predictors of mortality and neurologic disability 90 days after stroke. Methods: Patients with up to 24 hours of stroke were prospectively recruited. An ECG was taken at the time of admission. The patients' clinical evolution was evaluated during hospitalization and after discharge by means of a prescheduled return in 90 days. The degree of disability was measured by the modified Rankin scale (mRs). In relation to the mRs, patients were divided into those with scores from 0 to 2 and those with scores equal to or greater than 3 at the end of the observation period. Results: Of the 112 patients studied, 29 (25.8%) died during the study period. Patients who died presented higher National Institute of Health Stroke Scale and mRs scores on admission, elevated biomarkers of myocardial necrosis, and abnormalities on the ECG. The prevalence of ECG abnormalities was 63%. A logistic regression model showed that strain pattern and T-wave alterations were predictors of mortality (odds ratio [OR]: 12.970, 95% confidence interval [CI]: 1.519-110.723, P =.019; OR: 3.873, 95% CI: 1.135-13.215, P =.031, respectively) and mRs at 90 days (OR: 12.557, 95% CI: 1.671-94.374, P =.014; OR: 15.970, 95% CI: 3.671-69.479, P
- Subjects :
- Male
medicine.medical_specialty
Clinical Investigations
Myocardial Ischemia
030204 cardiovascular system & hematology
electrocardiogram
Logistic regression
outcomes
Electrocardiography
03 medical and health sciences
0302 clinical medicine
Risk Factors
Modified Rankin Scale
Internal medicine
Humans
Medicine
cardiovascular diseases
030212 general & internal medicine
Stroke
Aged
Retrospective Studies
Aged, 80 and over
business.industry
Stroke scale
General Medicine
Odds ratio
prediction
Middle Aged
Stroke subtype
Prognosis
medicine.disease
mortality
stroke
Confidence interval
neurologic disability
Survival Rate
Strain pattern
Cardiology
Female
Hydroxymethylglutaryl-CoA Reductase Inhibitors
Cardiology and Cardiovascular Medicine
business
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Scopus, Repositório Institucional da UNESP, Universidade Estadual Paulista (UNESP), instacron:UNESP, Clinical Cardiology
- Accession number :
- edsair.doi.dedup.....a3556fae2d611d37b52305f5f83a80ff