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Estudio endoscópico en familiares de primer grado de pacientes operados por cáncer colorrectal

Authors :
Demian A Fullerton
Eliana Pinto T
Gonzalo Soto D
Francisco López-Köstner
Johanna Argandoña
Udo Kronberg
Vanesa Miranda B
Álvaro Zúñiga D
Source :
Revista médica de Chile v.134 n.8 2006, SciELO Chile, CONICYT Chile, instacron:CONICYT
Publication Year :
2006
Publisher :
SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2006.

Abstract

Background: First degree relatives of patients with colorectal carcinoma are at a higher risk of having the disease than the general population. Therefore, they should be subjected to screening colonoscopy. Aim: To assess the effectiveness of colonoscopy among first degree relatives of patients with colorectal carcinoma. Material and methods: A free colonoscopy was offered to first degree relatives of patients operated on for colorectal cancer between 1998 and 2000. As inclusion criteria, subjects had to be asymptomatic, older than 40 years or less than 10 years younger than the index case. Each subject was contacted twice, inviting him/her to have a colonoscopy performed. Results: Two hundred forty three relatives were contacted for the study and in 76, a colonoscopy was performed. Among the latter, a neoplasm was found in 13 (17%): One adenocarcinoma and 12 adenomas. Three of these lesions were located in the right colon. The main reason given by the 176 subjects that did not agree to have a colonoscopy was lack of interest. Conclusions: Screening colonoscopy is effective to detect adenoma and adenocarcinomaamong first degree relatives of patients with colorectal carcinoma, however only 31% of all potential relatives agreed to undergo a colonoscopy (Rev Med Chile 2006; 134: 997-1001). (Key words: Colonic neoplasms; Colonoscopy; Rectal neoplasms)

Details

ISSN :
00349887
Volume :
134
Database :
OpenAIRE
Journal :
Revista médica de Chile
Accession number :
edsair.doi.dedup.....a3416d9b195af07ba6834f157e0d41a9