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Experimental and analytical evaluation on the mass transfer performance of braided stent-grafts

Authors :
Fujun Wang
Jing Lin
Xuan Fang
Wen Xue
Lu Wang
Fan Zhao
Guoping Guan
Jing Gao
Liheng Gao
Source :
Journal of the mechanical behavior of biomedical materials. 86
Publication Year :
2018

Abstract

Endoleak and luminal loss related to blood permeation and microthrombus migration remain the main challenges in the aneurysm treatment, although stent-grafts have been widely applied. Stent-grafts provide a boundary to shield blood and microemboli transport, which are correlated with their mass transfer performance. Water permeability of vascular prostheses with woven and knitted structures has been analyzed and documented by many researchers, as well as oxygen and protein transfer. However, it is almost a total lack of blood and microemboli transfer along the braided stent-graft thickness direction. In this research, we provided a methodology for the vascular prostheses mass transfer evaluation. Braided stent-grafts in our former research were conducted on a self-developed testing system to investigate their blood permeability and microthrombus transfer behaviors. The pressure along wall thickness direction can be changed. Analytical models were also established based on pore parameters, making them applicative to different structures. Results revealed that the mass transfer behavior of stent-grafts was positively affected by porosity and pore diameter while negatively influenced by their thickness.

Details

ISSN :
18780180
Volume :
86
Database :
OpenAIRE
Journal :
Journal of the mechanical behavior of biomedical materials
Accession number :
edsair.doi.dedup.....a33c9cfc0d26ba6bd0b7edb34f6a8366