Convenient Approach for the One-Pot, Three-Component Synthesis of 1-(Benzothiazolylamino)Methyl-2- Naphthol Using Citric Acid as a Green Catalyst

A straightforward, one-pot multicomponent synthesis of 1-(benzothiazolylamino)methyl-2-naphthol derivatives was achieved by condensation of 2-naphthol, aldehydes, and 2- aminobenzothiazole catalyzed by a small amount of citric acid, which acts as a benign enviermentally catalyst. Mild conditions with excellent yields and a simple isolation procedure are noteworthy advantages of this method.