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Dietary factors and alcoholic cirrhosis
- Source :
- Alcoholism, clinical and experimental research. 10(3)
- Publication Year :
- 1986
-
Abstract
- Mortality from cirrhosis in many countries deviates markedly from that expected for a given per capita alcohol intake. We investigated the possibility that dietary factors might explain the deviation expected and actual mortality rates in different countries. Deviations from expected cirrhosis mortality was calculated as a percentage for 17 different countries, all of whom had carrier rates for hepatitis B virus of less than 2%. The percentage of deviation was correlated with dietary intake of saturated fat, polyunsaturated fat, cholesterol, and also with mortality from ischemic heart disease. The percentage of deviation correlated inversely with dietary cholesterol (r = -0.86, p 0.001) and saturated fat (r = -0.80, p 0.001) and positively with polyunsaturated fats (r = -0.55 p 0.05). This suggests that both saturated fat and cholesterol protect against alcoholic cirrhosis while polyunsaturated fats promote cirrhosis. The correlation between percentage of deviation and ischemic heart disease (r = -0.78, p 0.002) suggests that those factors that promote ischemic heart disease protect against alcoholic cirrhosis.
- Subjects :
- Risk
Alcoholic liver disease
medicine.medical_specialty
Cirrhosis
Arteriosclerosis
Saturated fat
Medicine (miscellaneous)
Dietary factors
Coronary Disease
Toxicology
medicine.disease_cause
Cholesterol, Dietary
chemistry.chemical_compound
Polyunsaturated fat
Liver Cirrhosis, Alcoholic
Internal medicine
medicine
Humans
Hepatitis B virus
business.industry
Cholesterol
Mortality rate
medicine.disease
Dietary Fats
Psychiatry and Mental health
Endocrinology
chemistry
Fatty Acids, Unsaturated
business
Subjects
Details
- ISSN :
- 01456008
- Volume :
- 10
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Alcoholism, clinical and experimental research
- Accession number :
- edsair.doi.dedup.....a2cbc2b2df635ff7bcdcb64949dae5cf