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Roux Limb Motility in Gastric Bypass Patients with Chronic Abdominal Pain—Is There an Association to Prescribed Opioids?
- Source :
- Obesity surgery, New York : Springer, 2019, vol. 29, no. 12, p. 3860-3867
- Publication Year :
- 2019
- Publisher :
- Springer Science and Business Media LLC, 2019.
-
Abstract
- Background/Aim A number of patients continue to suffer from chronic abdominal pain of unknown origin, which may also lead to a prolonged use of opioid analgesics. Symptoms of abdominal pain, nausea and vomiting in this patient group resemble the characteristics of the Roux stasis Syndrome. The aim was to elucidate relationships between chronic abdominal pain, Roux limb motor activity and opioid analgesics. Methods Roux limb high-resolution manometry and ratings of abdominal pain and quality of life were analysed in 15 gastric bypass patients reporting abdominal pain of unknown origin. Effect of acute opiate administration (morphine i.v.) on fasting Roux limb motor activity was assessed in asymptomatic and morphine-naive gastric bypass patients (n = 9) and compared with an untreated control group (n = 11). Results In the symptomatic patient group, we found disturbed Roux limb motor patterns in 10 out of 15 examinations, but no signs of Roux stasis syndrome. A high prevalence of prescribed opioid analgesics as well as a high number of reoperations in this group. The worst quality of life and the highest number of pain-killing medications were observed among the patients with distal pacemaker activity in Roux limb. In the morphine-naive and asymptomatic patients, morphine increased the muscular tone in the Roux limb during phase III-like motor activity. Summary and Conclusions A majority of the RYGBP patients with chronic abdominal pain had a disturbed Roux limb fasting motility, and there was a high prevalence of prescribed opioid analgesics. In opiate-naive RYGBP patients, acute morphine intravenously increased the muscular tone of the Roux limb.
- Subjects :
- Adult
Male
Abdominal pain
Nausea
Endocrinology, Diabetes and Metabolism
Gastric bypass
Gastric Bypass
030209 endocrinology & metabolism
Asymptomatic
03 medical and health sciences
Postoperative Complications
0302 clinical medicine
Quality of life
Risk Factors
medicine
Humans
Pain Measurement
Retrospective Studies
Pain, Postoperative
Nutrition and Dietetics
business.industry
nutritional and metabolic diseases
Middle Aged
humanities
Abdominal Pain
Obesity, Morbid
Bariatric surgery
Anastomosis, Roux-en-Y
Gastrointestinal motility
drug therapy
Chronic pain
Analgesics, opioid
therapeutic use
administration&dosage
Analgesics, Opioid
surgical procedures, operative
Case-Control Studies
Anesthesia
Quality of Life
Vomiting
Morphine
616-056.52-089. [udc]
Female
030211 gastroenterology & hepatology
Surgery
Chronic Pain
medicine.symptom
Opiate
Gastrointestinal Motility
business
medicine.drug
Subjects
Details
- ISSN :
- 17080428 and 09608923
- Volume :
- 29
- Database :
- OpenAIRE
- Journal :
- Obesity Surgery
- Accession number :
- edsair.doi.dedup.....a2c0a4c996448bf18dcc2de7918c4c37