Back to Search
Start Over
The effects of ablation of the visual cortical area on the formation of LTP in the superior colliculus of the rat
- Source :
- Brain research. 537(1-2)
- Publication Year :
- 1990
-
Abstract
- Postsynaptic potentials (PSPs) were recorded on the surface of the rat in the superior colliculus (SC) after electrical stimulation of the optic nerve. Long-term potentiation (LTP) was elicited in the PSP by tetanic stimulation of the optic nerve either when the ipsilateral visual cortex was removed or when a GABA antagonist, picrotoxin, was administered before the tetanic stimulation. These results suggest that the corticotectal tract may inhibit the appearance of LTP via the GABAergic interneurons within the superficial gray layer (SGL).
- Subjects :
- Male
Superior Colliculi
genetic structures
Stimulation
Synaptic Transmission
chemistry.chemical_compound
Postsynaptic potential
Interneurons
Animals
Picrotoxin
Molecular Biology
Evoked Potentials
gamma-Aminobutyric Acid
Visual Cortex
musculoskeletal, neural, and ocular physiology
General Neuroscience
Superior colliculus
Optic Nerve
Rats, Inbred Strains
GABA receptor antagonist
eye diseases
Electric Stimulation
Rats
nervous system
chemistry
Optic nerve
GABAergic
Neurology (clinical)
Tetanic stimulation
Neuroscience
Developmental Biology
Subjects
Details
- ISSN :
- 00068993
- Volume :
- 537
- Issue :
- 1-2
- Database :
- OpenAIRE
- Journal :
- Brain research
- Accession number :
- edsair.doi.dedup.....a2bef72991ceb6416c31ef24131029f6