Back to Search
Start Over
Oxygen saturation and perfusion index screening in neonates at high altitudes: can PDA be predicted?
- Source :
- European Journal of Pediatrics. 180:31-38
- Publication Year :
- 2020
- Publisher :
- Springer Science and Business Media LLC, 2020.
-
Abstract
- Screening critical congenital heart disease in neonates with 24-48 h of age could be made by oxygen saturation determination. Perfusion index may be used as an adjunct to pulse oximetry screening to detect non-cyanotic critical congenital heart disease cases such as a left heart outflow obstruction. We evaluate the results of combined screening for oxygen saturation and peripheral perfusion index at high altitudes. The study included 501 neonates older than gestational week 35. The mean oxygen saturation was lower than at sea level, and the screening test was positive in a total of 21 (4.2%) babies. Critical congenital heart diseases were not detected in any patient. A total of 10 (2%) babies were detected with PDA, nine (1.8%) of whom recorded a positive screening test. The prevalence of PDA was significantly higher in the positive screening test group when compared with those who underwent echocardiography due to clinical findings.Conclusion: The median peripheral perfusion index at high altitude was not lower than at sea level, while the mean oxygen saturation, in contrast, was lower than at sea level. The low partial oxygen pressure found at high altitudes leads to a variation in postnatal adaptation and an increased prevalence of PDA. Accordingly, oxygen saturation screening may serve to identify babies with PDA at high altitudes. What is Known: • Oxygen saturation is known to be low at high altitudes, and thus the rates of false positivity are high when screening for critical congenital heart disease. • High altitudes are also associated with an increased prevalence of simple congenital heart disease. What is New: • The peripheral perfusion index at high altitude is not lower than at sea level. • The prevalence of PDA is significantly higher in those with false positive screening results.
- Subjects :
- Heart Defects, Congenital
medicine.medical_specialty
Heart disease
Perfusion index
Partial oxygen
03 medical and health sciences
0302 clinical medicine
030225 pediatrics
Internal medicine
medicine
Humans
Oximetry
030212 general & internal medicine
Critical congenital heart disease
Oxygen saturation (medicine)
medicine.diagnostic_test
business.industry
Altitude
Infant, Newborn
Effects of high altitude on humans
medicine.disease
Oxygen
Perfusion Index
Pulse oximetry
Pediatrics, Perinatology and Child Health
Cardiology
Gestation
business
Subjects
Details
- ISSN :
- 14321076 and 03406199
- Volume :
- 180
- Database :
- OpenAIRE
- Journal :
- European Journal of Pediatrics
- Accession number :
- edsair.doi.dedup.....a299ff08d30b95128a5c8ef7138fbbb7