Role of sLOX‐1 in intracranial artery stenosis and in predicting long‐term prognosis of acute ischemic stroke

Objective The role of sLOX‐1 in acute ischemic stroke still remains unclear. This study aims to demonstrate the value of sLOX‐1 in evaluating degrees of intracranial artery stenosis and to predict prognosis in stroke. Methods Two hundred and seventy‐two patients were included in this study and basic data were collected within 72 hr on admission. We assessed the association between sLOX‐1 levels and stroke conditions in one‐year duration. After adjusting for potential confounders, regression analyses were performed. Results We found that sLOX‐1 levels were increased significantly in severe patients compared to the mild stroke group (p = .011). After adjusting confounders, sLOX‐1 was associated with a poor functional outcome in patients with an adjusted OR of 2. 946 (95% CI, 1.788–4.856, p