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Rhegmatogenous retinal detachment in Scotland: research design and methodology
- Source :
- BMC Ophthalmology, Vol 9, Iss 1, p 2 (2009), BMC Ophthalmology, Mitry, D, Charteris, D G, Yorston, D, Fleck, B W, Wright, A, Campbell, H & Singh, J 2009, ' Rhegmatogenous retinal detachment in Scotland : Research design and methodology ', BMC Ophthalmology, vol. 9, no. 1, pp. 2 . https://doi.org/10.1186/1471-2415-9-2
- Publication Year :
- 2009
- Publisher :
- BMC, 2009.
-
Abstract
- Background Rhegmatogenous retinal detachment (RRD) is a potentially blinding condition and a common cause of ocular morbidity. Establishing an accurate estimate of disease incidence and distribution is an important first step in assessing the healthcare burden related to this condition and in subsequent planning and provision of treatment strategies. The aim of this study is to obtain a first estimate incidence of RRD in Scotland, to estimate the incidence of familial RRD and to describe the known associations of RRD within the study population. Methods/Design We have established a national prospective observational study seeking to identify and recruit all incident cases of RRD in the Scottish population over a 2 year period. After fully informed consent, all participants will have a blood sample taken and a full medical history and clinical examination performed including visual acuity, refraction, slit-lamp examination, intra-ocular pressure measurement and detailed fundal examination. We describe the study design and protocol. Conclusion This study will provide the first estimate of the annual incidence of RRD in Scotland. The findings of this study will be important in estimating the burden of disease and in the planning of future health care policy related to this condition. This study will also establish a genetic resource for a genome wide association study to investigate if certain genetic variants predispose to RRD.
- Subjects :
- Research design
Blinding
Population
Physical examination
Study Protocol
Clinical Protocols
lcsh:Ophthalmology
Informed consent
Myopia
Prevalence
Medicine
Humans
Medical history
Genetic Predisposition to Disease
education
education.field_of_study
medicine.diagnostic_test
business.industry
Incidence (epidemiology)
Incidence
Retinal Degeneration
Retinal Detachment
Genetic Variation
General Medicine
eye diseases
Ophthalmology
Scotland
lcsh:RE1-994
Case-Control Studies
Epidemiologic Research Design
Optometry
Observational study
business
Genome-Wide Association Study
Subjects
Details
- Language :
- English
- ISSN :
- 14712415
- Volume :
- 9
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- BMC Ophthalmology
- Accession number :
- edsair.doi.dedup.....a24f6e8493845888f7ce9778c4e9efcd