Additional file 1 of Development of artesunate intelligent prodrug liposomes based on mitochondrial targeting strategy

Additional file 1: Fig. S1. Chemical structure of SS-ATS and number of carbon atoms in SS-ATS. Fig. S2. Chemical structure of TPP-SS-ATS and number of carbon atoms in TPP-SS-ATS. Fig. S3. Mass spectrum of SS-ATS. Fig. S4. Mass spectrum of TPP-SS-ATS. Fig. S5. 1H NMR spectrum of SS-ATS. Fig. S6. 1H NMR spectrum of TPP-SS-ATS. Fig. S7. 13C NMR spectrum of TPP-SS-ATS. Fig. S8. HSQC spectrum of TPP-SS-ATS. Fig. S9. HMBC spectrum of TPP-SS-ATS. Fig. S10. Purity check of TPP-SS-ATS chromatogram. Fig. S11. Ultraviolet spectrogram of TPP-SS-ATS. Fig. S12. Molecular dynamics simulation. Fig. S13. The hemolytic results of TPP-SS-ATS-LS. Fig. S14. Effect of TPP-SS-ATS -LS on oxygen consumption rate (OCR) of human breast MCF-7 cells. Fig. S15. Effect of TPP-SS-ATS-LS on oxygen consumption rate (OCR) of mouse breast 4T1 cells. Table S1. Result of TPP-SS-ATS purity check.