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Coupled near-field and far-field exposure assessment framework for chemicals in consumer products
- Source :
- Fantke, P, Ernstoff, A, Huang, L, Csiszar, S A & Jolliet, O 2016, ' Coupled near-field and far-field exposure assessment framework for chemicals in consumer products ', Environment International, vol. 94, pp. 508-518 . < http://www.sciencedirect.com/science/article/pii/S0160412016302288 >, Environment International, Vol 94, Iss, Pp 508-518 (2016), Technical University of Denmark Orbit
- Publication Year :
- 2016
-
Abstract
- Humans can be exposed to chemicals in consumer products through product use and environmental emissions over the product life cycle. Exposure pathways are often complex, where chemicals can transfer directly from products to humans during use or exchange between various indoor and outdoor compartments until sub-fractions reach humans. To consistently evaluate exposure pathways along product life cycles, a flexible mass balance-based assessment framework is presented structuring multimedia chemical transfers in a matrix of direct inter-compartmental transfer fractions. By matrix inversion, we quantify cumulative multimedia transfer fractions and exposure pathway-specific product intake fractions defined as chemical mass taken in by humans per unit mass of chemical in a product. Combining product intake fractions with chemical mass in the product yields intake estimates for use in life cycle impact assessment and chemical alternatives assessment, or daily intake doses for use in risk-based assessment and high-throughput screening. Two illustrative examples of chemicals used in personal care products and flooring materials demonstrate how this matrix-based framework offers a consistent and efficient way to rapidly compare exposure pathways for adult and child users and for the general population. This framework constitutes a user-friendly approach to develop, compare and interpret multiple human exposure scenarios in a coupled system of near-field (‘user’ environment), far-field and human intake compartments, and helps understand the contribution of individual pathways to overall human exposure in various product application contexts to inform decisions in different science-policy fields for which exposure quantification is relevant. Keywords: Near-field consumer exposure, Multimedia multi-pathway framework, Product intake fraction, Life cycle impact assessment, Chemical alternatives assessment, High-throughput risk screening
- Subjects :
- Engineering
Chemical alternatives assessment
010504 meteorology & atmospheric sciences
Life cycle impact assessment
Product intake fraction
Daily intake
Population
Cosmetics
010501 environmental sciences
01 natural sciences
Risk Assessment
Product lifecycle
Environmental Science(all)
Floors and Floorcoverings
High-throughput risk screening
Humans
Product (category theory)
education
lcsh:Environmental sciences
0105 earth and related environmental sciences
General Environmental Science
Exposure assessment
Near-field consumer exposure
lcsh:GE1-350
education.field_of_study
business.industry
Environmental engineering
Environmental Exposure
Models, Theoretical
Unit mass
Human exposure
Biochemical engineering
business
Multimedia multi-pathway framework
Environmental Monitoring
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Fantke, P, Ernstoff, A, Huang, L, Csiszar, S A & Jolliet, O 2016, ' Coupled near-field and far-field exposure assessment framework for chemicals in consumer products ', Environment International, vol. 94, pp. 508-518 . < http://www.sciencedirect.com/science/article/pii/S0160412016302288 >, Environment International, Vol 94, Iss, Pp 508-518 (2016), Technical University of Denmark Orbit
- Accession number :
- edsair.doi.dedup.....a2352a1752dccbf45017596424ac4057