Kakelokelose, a sulfated mannose polysaccharide with anti-HIV activity from the Pacific tunicate Didemnum molle

Authors :: Raffaele Riccio
Robin B. Kinnel
Giuseppe Bifulco
Paul J. Scheuer
Source :: ResearcherID
Abstract: An unusual sulfated mannose homopolysaccharide (1) showing in vitro anti-HIV activity has been isolated from the mucous secretion of the Pacific tunicate Didemnum molle. Analysis of 1H and 13C NMR data of the polysaccharide and its desulfated derivative 2 revealed that it consists of a sequence of 2,3-disulfated mannose units joined through β (1,6) glycosidic linkages.

Subjects :: chemistry.chemical_classification
biology
Organic Chemistry
Mannose
Glycosidic bond
biology.organism_classification
Polysaccharide
Biochemistry
In vitro
Tunicate
Homopolysaccharide
chemistry.chemical_compound
Sulfation
chemistry
Drug Discovery
Didemnum molle

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