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Supplementary Table and Supplementary Figures 1 through 4 from Differential and Common DNA Repair Pathways for Topoisomerase I- and II-Targeted Drugs in a Genetic DT40 Repair Cell Screen Panel

Authors :
Junko Murai
Yves Pommier
Shunichi Takeda
Tsuneharu Miki
Terukazu Nakamura
Toshiaki Kogame
Toru Fukushima
Hiroyasu Shimizu
Yuko Maede
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

PDF - 7482KB, Supplementary Table 1. DT40 isogenic mutant cell lines used in this study. Cell lines are ordered as in Figure 1. Supplementary Figure 1. Generation of the ATG5-deficient DT40 cells. Supplementary Figure 2. Linearity between cells per well and luminescent signal. Supplementary Figure 3. Representative survival curves and corresponding cell cycle analyses. Supplementary Figure 4. Sensitivity profile of paclitaxel (Taxol) in the DT40 repair panel. Data are plotted as in Figure 1. References to Supplementary Table 1.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....a1f7100595cc9f5c8b926ecfd8f20e86
Full Text :
https://doi.org/10.1158/1535-7163.22503661