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Clinical variables accompanying salt-sensitive essential hypertension in ethnic Kashmiri population

Authors :
Javaid, Chachoo
Nausheen, Mushtaq
Sami, Jan
Sabhiya, Majid
Iqbal, Mohammad
Source :
Journal of Hypertension. 40:916-923
Publication Year :
2022
Publisher :
Ovid Technologies (Wolters Kluwer Health), 2022.

Abstract

Salt sensitivity is actually a measure of an individual's blood pressure response to salt intake. It has been reported that people who are salt sensitive have high prevalence of hypertension and target organ damage. The link between dietary salt intake and hypertension is well established, and a reduction in salt intake has been shown to lower blood pressure.In Kashmir, this achieves significance because of a high incidence of hypertension along with a high salt intake among ethnic Kashmiris.We analysed clinical variables accompanying salt sensitive hypertension among Kashmiri population in our on-going salt sensitivity study on 770 Kashmiri patients (250 men, 520 women) of age group 18years and above from March 2020 to June 2021. We studied the clinical variables accompanying salt sensitivity and the difference in their blood pressure on. a low salt diet (mean = 2 g/day) vs. their usual salt intake (mean = 11 g/day). To document compliance of salt-restricted diet, we used 24-h urinary NaCl estimation as a surrogate marker for salt intake estimation.We observed, a huge drop in SBP (-28.9 mmHg), DBP (-17.6 mmHg) and mean arterial pressure (-21.3mmHg) in this cohort of 770 ethnic Kashmiris on a strict salt restricted diet. And that women, urban inhabitants, and nonsmokers are more prone to the risk of developing salt sensitive hypertension. Physical activity had no effect on salt sensitivity.As per our study, salt restriction has a major role in treatment of Hypertension in Kashmiri Population. More studies need to be focused on this vital area.

Details

ISSN :
14735598 and 02636352
Volume :
40
Database :
OpenAIRE
Journal :
Journal of Hypertension
Accession number :
edsair.doi.dedup.....a1e593413818c451b0a1574d9f946bd8
Full Text :
https://doi.org/10.1097/hjh.0000000000003093