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Supplemental Tables S1-S12 from Genomic and Transcriptomic Analysis of Relapsed and Refractory Childhood Solid Tumors Reveals a Diverse Molecular Landscape and Mechanisms of Immune Evasion

Authors :
Jeffrey M. Trent
Giselle L. Saulnier Sholler
Javed Khan
Rebecca F. Halperin
Jonathan J. Keats
Szabolcs Szelinger
Bryce Turner
Austin Christofferson
Faith Cisneros
Apurva M. Hegde
Daniel Enriquez
Tyler Izatt
Sara Nasser
Alison Roos
Hue V. Reardon
Xinyu Wen
Jun S. Wei
Hsien-Chao Chou
Jeffrey Bond
Karl Dykema
Elizabeth VanSickle
Genevieve Bergendahl
Virginia L. Harrod
Peter E. Zage
Kathleen Neville
Jawhar Rawwas
Randal K. Wada
Javier E. Oesterheld
Michael S. Isakoff
William Roberts
Albert Cornelius
Deanna Mitchell
Don E. Eslin
Valerie I. Brown
William S. Ferguson
Jacqueline M. Kraveka
Abhinav B. Nagulapally
William P.D. Hendricks
Sara A. Byron
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Table S1. Extended Cohort Annotations. Table S2. Mutational Signatures. Table S3. GISTIC Copy Number Analysis. Table S4. Somatic Variants in Relapsed/Refractory Childhood Solid Tumors (n=184 Patients with T/N WES). Table S5. Clinvar Pathogenic and Likely Pathogenic Germline Variants in Relapsed/Refractory Childhood Solid Tumors(n=184 Patients with T/N WES). Table S6. Gene Lists. Table S7. Log2(TPM+1) Values for the 2,199 Most Variable Genes Expressed Across the Cohort of Relapsed/Refractory Childhood Solid Tumors with RNA-seq (n=245). Table S8. Differential Expression Analysis of 2,199 Most Variable Genes Among Clusters. Table S9. Genes Filtered for COSMIC, Transcription Factors and Potential Drug Targets from Table S8 with log2FC greater than or equal to 2. Table S10. Differential Expression Analysis Among C3a, C3b, and C3c Subclusters. Table S11. Samples Falling in Clusters C3a-C3c and Genes that are Uniformly Highly Expressed in the Clusters. Table S12. Longitudinal Samples.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....a1e39ae7fd69f2b814d3c10f93f7f3e1