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Molecular profiling of Peru Balsam reveals active ingredients responsible for its pharmaceutical properties
- Source :
- Natural Product Research, Natural Product Research, Taylor & Francis, 2020, pp.1-6. ⟨10.1080/14786419.2020.1753056⟩, Natural Product Research, 2020, pp.1-6. ⟨10.1080/14786419.2020.1753056⟩
- Publication Year :
- 2020
- Publisher :
- HAL CCSD, 2020.
-
Abstract
- Peru Balsam, a resinous substance derived from Myroxylon balsamum var. pereirae, has historically been used as a topical ointment for various skin conditions such as scabies, poorly healing wounds, eczema, and haemorrhoids. The ingredients responsible for these properties are not fully elucidated. We investigated the chemical composition of two Peru Balsam samples, one historical and one modern, using gas chromatography/mass spectrometry to identify the active ingredients responsible for its pharmaceutical properties. Both Peru Balsam specimens investigated had similar compositions, showing the stability of the substance. Components identified are effective against scabies, exhibit antimicrobial activity and aid skin penetration. These properties are consistent with historical uses of Peru Balsam. Several ingredients are also known allergens. This study, combining chemical information with scientific literature related to pharmaceutical properties of natural substances, represents a breakthrough in the elucidation of active ingredients in Peru Balsam.
- Subjects :
- Myroxylon balsamum
Peru Balsam
Plant Science
Q1
01 natural sciences
Biochemistry
gas chromatography/mass spectrometry
Analytical Chemistry
Ointments
allergy
antimicrobial
Meso- and Southern America
Peru
Humans
Medicine
Healing wounds
ComputingMilieux_MISCELLANEOUS
Active ingredient
[SDV.EE]Life Sciences [q-bio]/Ecology, environment
Balsams
Myroxylon
integumentary system
Traditional medicine
010405 organic chemistry
business.industry
Organic Chemistry
Antimicrobial
R1
3. Good health
0104 chemical sciences
010404 medicinal & biomolecular chemistry
Dermatitis, Allergic Contact
Peru balsam
business
Topical ointment
Subjects
Details
- Language :
- English
- ISSN :
- 14786419 and 10292349
- Database :
- OpenAIRE
- Journal :
- Natural Product Research, Natural Product Research, Taylor & Francis, 2020, pp.1-6. ⟨10.1080/14786419.2020.1753056⟩, Natural Product Research, 2020, pp.1-6. ⟨10.1080/14786419.2020.1753056⟩
- Accession number :
- edsair.doi.dedup.....a1c860bc585b14cd78a80fb0d8908ab4